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Table of Contents | |
FOLIC ACID OR FOLATE
- Folic acid is rather unique in hyperthyroidism, because scientists have
found that it is one vitamin that is not low in the blood of hypers. For
this reason I do not think it's as necessary to supplement folic acid as the
other B vitamins.
Recently I discovered that folic acid is now being added to many grain
products. I'm not sure of the exact date that this federal program began,
but it makes me a little suspicious of whether this added folic acid could
be depleting other essential B vitamins and therefore contributing to the
development of hyperT in persons who consume a high grain or high
carbohydrate diet. -
- It's possible that the addition
of other nutritional supplements to foods may also contribute to thyroid
disease. For example, iron is added to many food products, especially
breakfast cereals, breads, and other grain products. We know that excess
iron will deplete copper, so it's possible that eating iron fortified foods
is a contributing factor to hyperthyroidism.
-
- It
would be a long shot if excess folic acid supplementation were a factor, but
who knows? I'll look into this a little deeper. Here is the article from Dr.
Mercola's site, www.mercola.com, where
I learned that folic acid is being added to foods:
Folic Acid Fortification Making A Dent
The policy of adding folic
acid to grain foods--including cereals, breads, pasta and
flour--instituted just 3 years ago by the US Food and Drug Administration
(FDA) appears to be a success.
Blood samples taken after folic acid supplementation
show a 38% higher level of
folate than samples taken before folic acid fortification; 96% of the people
who had blood drawn after supplementation had acceptable folate levels.
Among the people who had blood drawn before fortification, 87% had
acceptable folate levels.
The government decided to mandate folic acid
fortification as part of an effort to reduce the number of children born
with neural tube defects, a type of birth defect that affects the brain and
spinal cord and includes spina bifida.
Results of earlier
studies demonstrated that folic acid supplementation before pregnancy and
during the first weeks of pregnancy could reduce the risk of these defects.
The neural tubes close at about week 3 or 4 of
pregnancy, so many women don't even know they are pregnant at that early
stage. Initially, the government campaigned to simply have women of
childbearing age routinely take folic acid supplements but compliance was
very low. That's when the FDA decided to order mandatory fortification, she
said.
Annual Meeting Of The
Federation Of American Societies For Experimental Biology In Orlando, FL
April 1, 2001
Nutr Rev 1999 Oct;57(10):314-21 |
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Folate and cancer prevention: a new medical application
of folate beyond hyperhomocysteinemia and neural tube defects.
Kim YI
Department of Medicine, St. Michael's Hospital, Toronto, Ontario, Canada.
Folate is an important cofactor in the transfer of one-carbon moieties
and plays a key role in DNA synthesis, repair, and methylation. The role
of folate has greatly evolved from the prevention of macrocytic anemia to
the prevention of cardiovascular disease and neural tube defects. More
recently, epidemiologic, animal, and clinical evidence suggests that folate
may also play a role in cancer prevention. Two recently published large,
prospective epidemiologic studies suggest that maintaining adequate levels
of serum folate or moderately increasing folate intakes from dietary sources
and vitamin supplements can significantly reduce the risk of pancreatic and
breast cancer, respectively. This protective effect of folate appears to be
operative in subjects at risk for developing these cancers, namely, male
smokers for pancreatic cancer and women regularly consuming a moderate
amount of alcohol for breast cancer. Because the expanding role of
folate nutrition in cancer prevention has major public health implications,
research is required to clearly elucidate the effect of folate on
carcinogenesis.
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