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Table of Contents | |
LUTEIN
- Following is a study mentioning that lutein may help macular
degeneration.
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Invest Ophthalmol Vis Sci 2001 Feb;42(2):439-446 |
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Macular Pigment and Risk for Age-Related Macular
Degeneration in Subjects from a Northern European Population.
Beatty S, Murray IJ, Henson DB, Carden D, Koh HH, Boulton ME
University Department of Ophthalmology, Manchester Royal Eye Hospital,
Manchester. Visual Sciences Laboratory, Department of Optometry and
Neuroscience, University of Manchester Institute of Science and Technology,
Manchester. Department of Optometry and Vision Sciences, Cardiff University,
United Kingdom.
[Record supplied by publisher]
PURPOSE. Age and advanced disease in the fellow eye are the two most
important risk factors for age-related macular degeneration (AMD). In this
study, the authors investigated the relationship between these variables and
the optical density of macular pigment (MP) in a group of subjects from a
northern European population. METHODS. The optical density of MP was
measured psychophysically in 46 subjects ranging in age from 21 to 81 years
with healthy maculae and in 9 healthy eyes known to be at high-risk of AMD
because of advanced disease in the fellow eye. Each eye in the latter group
was matched with a control eye on the basis of variables believed to be
associated with the optical density of MP (iris color, gender, smoking
habits, age, and lens density). RESULTS. There was an age-related decline in
the optical density of macular pigment among volunteers with no ocular
disease (right eye: r(2) = 0.29, P: = 0.0006; left eye: r(2) = 0.29, P: <
0.0001). Healthy eyes predisposed to AMD had significantly less MP than
healthy eyes at no such risk (Wilcoxon's signed rank test: P: = 0.015).
CONCLUSIONS. The two most important risk factors for AMD are associated with
a relative absence of MP. These findings are consistent with the hypothesis
that supplemental lutein and zeaxanthin may delay, avert, or modify
the course of this disease.
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