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CARNITINE
- Supplementation with the amino acid carnitine may help with some of the
symptoms of hyperthyroidism. As the following study indicates, carnitine
excretion is accelerated in hyperthyroidism. There is a report that some
hypers have been helped by carnitine, although I did not find carnitine to
be significantly helpful for me during hyperthyroidism.
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Metabolism 1977 Apr;26(4):351-6 |
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Urinary excretion of carnitine in patients with
hyperthyroidism and hypothyroidism: augmentation by thyroid hormone.
Maebashi M, Kawamura N, Sato M, Imamura A, Yoshinaga K
Urinary excretion of carnitine and serum concentrations of carnitine,
triglyceride, and free fatty acids were measured in 54 hyperthyroid and 13
hypothyroid patients, and the results were compared with those of normal
subjects. In hyperthyroid patients urinary excretion of carnitine was highly
increased above that of the control subjects. On adequate treatment with
antithyroid drug, carnitine excretion was reduced to the normal range, and
serum lipids changed in parallel. In contrast, carnitine excretion was
markedly reduced in hypothyroid patients. After substitution therapy with
thyroid hormones the excretion increased in these patients. This change was
associated with a marked reduction of serum triglyceride. There was an
inverse correlation between urinary excretion of carnitine and serum
triglyceride concentration. Carnitine excretion was significantly correlated
with serum thyroxine concentration in hyper- and hypothyroid patients. The
results suggest that thyroid hormones play an important role in carnitine
metabolism, which in turn influences serum triglyceride metabolism.
Subj: [hyperthyroidism] L-carnitine and Graves'
Date: 1/10/01 3:52:04 AM Pacific Standard Time
From: redhengirl@aol.com
Reply-to: hyperthyroidism@egroups.com
To: hyperthyroidism@egroups.com
When I was experiencing a lot of bone/muscle pain after RAI, I tried Mega
L-carnitine based on an article I read. It really helped. I have no idea
why an amino acid would be helpful, but it did. I think that all theories
about our need for supplemental vitamins and minerals are definitely on the
right track.
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